Plain Ringer’s Solution

Description: A clear, sterile, and apyrogenic injectable solution.

Pharmacological Characteristics: Ringer’s solution is composed of sodium chloride, calcium chloride, and potassium chloride diluted in water for injection. The composition of this solution closely resembles that of extracellular fluids. Therefore, Ringer’s solution is intended for fluid and electrolyte replacement in situations where these losses occur.

Indications: Rehydration and restoration of hydroelectrolytic balance, when there is loss of fluids and chloride, sodium, potassium, and calcium ions.

Contraindications: Ringer’s Solution is contraindicated in cases of:

• Hypernatremia
• Hypercalcemia
• Hyperkalemia (hyperkalemia)
• Hyperchloremia

Dosage and Directions for Use:

• Dosage should be determined by a physician and depends on the patient’s age, weight, clinical condition, the medication diluted in the solution, and laboratory determinations.
• Before administration, parenteral solutions should be visually inspected for particulate matter, cloudiness, cracks, and any breaches in the primary packaging.

Important Warnings:

• PARENTERAL SOLUTIONS MUST BE ADMINISTERED BY QUALIFIED HEALTHCARE PROFESSIONALS. Self-medication or administration by untrained individuals can result in serious complications.
• ADMINISTRATION OF PARENTERAL SOLUTIONS REQUIRES CAREFUL ATTENTION TO PRESCRIBED DOSAGES. Errors in dilution or quantity administered can lead to serious or fatal adverse effects.
• PRODUCTS MUST BE STORED CORRECTLY IN ACCORDANCE WITH THE MANUFACTURER’S INSTRUCTIONS. Improper storage may lead to product contamination and loss of effectiveness.
• PARENTERAL SOLUTIONS MUST BE MONITORED AND ADMINISTRATION PROCESSED. Changes in parameters such as blood pressure, heart rate, and oxygen levels may indicate complications that require immediate intervention.
• DO NOT USE if the vial seal is broken or the medication is cloudy.
• DO NOT USE medication that has PASSED ITS VALIDITY PERIOD, as this may result in loss of therapeutic efficacy and risk of adverse effects.
• Vials should be used immediately after opening and SHOULD NOT BE STORED for future use.

Presentation:

• Sol. Inj. IV of Ringer – Box. 40 FR Plas. Trans. with 250mL – Closed Syst.
• Sol. Inj. IV of Ringer – Box. 24 FR Plas. Trans. with 500mL – Closed Syst.
• Sol. Inj. IV of Ringer – Box. 12 FR Plas. Trans. with 1000mL – Closed Syst.

Composition (per mL):

• Sodium chloride – NaCl (DCB 02421)…………..8.6 mg
• Potassium chloride – KCl (DCB 02415)…………..0.3 mg
• Calcium chloride – CaCl2.2H2O (DCB 02370)…0.33 mg
• Water for injection qsp ………………………………………1 mL

Electrolyte Content (per L):

• Sodium (Na+) …………………………………….147 – 147.5 mEq/L
• Potassium (K+)……………………………………….4 – 4.47 mEq/L
• Calcium (Ca2+)……………………………………4.47 – 4.5 mEq/L
• Chloride (Cl-)………………………………………………..156 mEq/L

Physical Properties:

• Osmolarity ……………………………………..309.7 mOsm/L
• pH………………………………………………………………..5.0 – 7.5

Validity Period:

24 months after the date of manufacture.